A synaptically localized lengthy noncoding RNA proves to be an vital regulator of neural plasticity.

Biomedical scientists have developed a brand new RNA-sequencing technique -- 'Panoramic RNA Show by Overcoming RNA Modification Aborted Sequencing,' or PANDORA-seq -- that may assist uncover quite a few modified small RNAs that had been beforehand undetectable.

Utilizing information from RNA-folding experiments, the researchers generated the first-ever data-driven motion pictures of how RNA folds as it's made by mobile equipment. By watching their movies of this folding happen, the researchers found that RNA typically folds in shocking, maybe unintuitive methods, akin to tying itself into knots.